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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e3ae38b7cc43e9673bdc403328d6025644f6e10b10b892edc85d78a462af8e' 
  AND token = '9Rmrf8kHa5P1/i8BK3W8wUj5wlO2liBTqt256ZwYdYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}