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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a645e3807cd0a89a3ad05bd4265763a6dde6c38efa432327cfb9206e583a0db4' 
  AND token = 'gVF2yS2VsPxIO0I1R3kQ/ZrlUmf8zCqSWNtt65D3eFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}