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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d50a2bf0d9ba13f390225ffb642a6a936031efcd0e3a2b1ce4e4f51381787dd' 
  AND token = '1joBuk0sB5+78jL7O6R+nEV4sevRR12abB43kBt4NHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}