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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1d65c6cd40ccd6260b02bb2c0500ed15519aa6fb9f03bedb6172ffb79c3f46' 
  AND token = 'Er9nV8vrgGDMQ733iVeoq2ADmpE08UgrYxIAe/MYXug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}