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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '391b5f4e6de9f46dd41a722590f3ff89669ddf1ae04178b78feb19e3b3d191ba' 
  AND token = '5EIQi4HuW30IP2lXuRqyQL5/ORRYTwoBCGq2MNrbpHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}