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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e42d7d8af3d8752cf45253bac2724ea4bda8b33a9c0a5273be8b2b31777698' 
  AND token = 'DODZuknVYozOkOaUVRUEos7KaX53ySnnYpjHn6QJ44g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}