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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506f1b1bee75218c06e7f22051afd57f6fb94609265f0d01e73d8298b7083b8b' 
  AND token = 'pmZDfK2WL2GDex24MJ7J5vaC/rRbs8y+mSs8uCskLlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}