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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ce0e8ca89db33b82d98202464fbde8faf5fa70b2141f2d5bd6075e7e5dbf9f' 
  AND token = 'YbsbBF0waCiFH7/4bGt42lx/yNT6zQSNeOfmTyt+GPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}