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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a563aa6af5c2ee72577cb629f018f7899e49c28c67a6896a62217f10ba6b2d6' 
  AND token = '/oeUXtJdKJfGqm5Jy2UtAtNwpG9NWCS04hPz6zxQmjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}