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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9893b2aaed655a4bcf05a98a7f68194981c2b143803a54d74f28e71cd177b341' 
  AND token = 'AK2L/ejx+ls5ekKPHlwNH3rbLTejEoyHbcfmUNvM5Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}