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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f421183ee0d862c8ce548411ac00376020f3e1a8a261a2a73283f6fa99b04a17' 
  AND token = 'xda76k+HpHzZKFVyO/B0XAl1DhiKT2BGsHxdx26tUgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}