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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294d87643efda447a2f252f793c5f7bfa32501b9b1b796c2726a2e9557f61c9e' 
  AND token = 'f1/rLlA0n/YNSZG1Rp2tD/s/diuBe27Nokr+21U2UQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}