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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b23c99188f00b3c54977d5b5cfe92cf2452ca025fca5b367030db3fc34df008' 
  AND token = 'cpR8DdT6O/UJHAY6HtuLmFUF4LBs10H03ARGjEZs4t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}