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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1579b48421bf76f0846820ae8354c5c9f568fe2a386a6953526bb6b1c6e23b8f' 
  AND token = 'JQRi0FohH9ri/UkZTQxTkd8l1sT9UOnADkX5T+Q9Enc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}