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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e24f50fd00d0cfd72dc08c216d0be53c3f99b7f7b65110a2054de7a09bf16c5' 
  AND token = 'KcHIyzGQNu4dIuufd/bmHUDit1eWmM36AJPWiPDML4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}