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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395176aba36a496c4bb5ba9fde364259ff6580ee57add58a1c410727f28e7f6d' 
  AND token = 'Dd64X+YZbyTMvNwl0S+pIjNSmFYZ6HvT4I2uAoZV3SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}