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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3444e834cb8bd0b89f539121f8a573345042d76d07d0e510402e6503b5526349' 
  AND token = 'r8ty7+sXDOrwb3vgD7OakW4SgETym9JcU47VLaLGjLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}