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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c163d43f0adbf3485f5ad3638a0f97ad6145651cf5f29ccce4bd969ad409e7f' 
  AND token = 'XqtyIt+PHLH2WyhBwbWnqmhHVka+LX8x1xkS5e9XStI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}