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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74cbd73a49dfa860894ddaaf52215c7c1ff3673bf021d8a939be6fc1a7cc46ab' 
  AND token = 'IEp3tgJL0rrOJ5X21PPXYlCXFR0TG5DQb5JVAKeqVhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}