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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4778b55471a39dc8ea02a313eb0d8d6a86dc079a4603d892b06b15cfb5af1dd2' 
  AND token = 'DoPmx0Pn3Ty59cn6/xd56qgjbCYNKcmeAsSA1qaySkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}