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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8842f1e8db39f955b5424f085b088bf1fa0569fdad36ef83648c528cda7d7613' 
  AND token = '46IimzKot2VV5+cB0ONSEmXsWU4yL0v3mqg+uGxeo8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}