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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572ab0590394a0077a04e0e2524b8e31ae651c824590d7708533853c36df8103' 
  AND token = 'LaeqMHInTnFAv9Me3udGWEZLcsMlFieBuUhH36XpnMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}