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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5750cfa0bfb133a9c4f9d42ec9e9c4befda7bb6adea1a888a1a405e8f36f797f' 
  AND token = '8mhZZb8snFc8FYCGOVN0luMY1zOwH8AhmZmbBorQ2zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}