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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b15109c05af88dd2f7616f66fb699f4120cc32e7e7f6f8e5d8a41e322e78c90' 
  AND token = '8XCIDJksGYeGue5L9n8hB9gvMyymGiBshqfFiyCAf4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}