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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a86df1178c9f1f4e83d379765f8cf5757504587faa45956cd21e729bb01cd0f2' 
  AND token = 'FSL44Bc9Due/wL6wgOHZfYHLHdj0/kHbww0MnCXF/Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}