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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb964e9ea014485a39f98e1cbf2c157ecf0eb6c13a8c2f025e5755b9dcc230a' 
  AND token = 's5kZeTNe/kPe0KxCzwAOS04JHnMHzwkll2PoRb+8poM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}