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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc42e6d63be4994760641f4671b4972f6a144301b6e775c294d08c2c65e8e287' 
  AND token = 'NqtI+vzGJf9M2dB/aeMT7uI99PUbipkAT53YOcbHlR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}