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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7120dcd25c628047741e7c4738cc107e5c18e4de1f421b344a9cd501b8fee059' 
  AND token = '6XESQZMF5aBRHfG5aPTrz4rdOYUGXpBm2vtqZUvA+xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}