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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c32f3347f51786637e6f04740f7691599c469a9730e3735bf5f6f6553a74e38' 
  AND token = 'ZY9iSmjw1brDHK1qjMmVFrfOYznYfQcp57ApgzJmZ6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}