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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c01e0a0aeb03505707a32341bf24a2de32fb2b2af5e910a3abe2913cb18e585' 
  AND token = 'xAxtXQWNOapNRhP55NHBFYxj90Mq4hb5WObk5WhAhSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}