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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb78a48f9a79c5d3b485c3ac3c6ff860455e17b0ab067b77d38695b0145192c5' 
  AND token = 'hx2Lid0asDfXZ/puQ6auzXXD2+mkoEtt06F8tb+QEfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}