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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28aec01bf4cd12c49b6f52fbb6ad79562309087245f62d57f1afb80b68e95a65' 
  AND token = 'uooUL2NVKsNHTrkcYVUY/3dNzbAvXRyjiBHLN7Raedc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}