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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c70a78e13f2c956b726332b0b3ea129d35415446cf5291c1d3e780f26534c08a' 
  AND token = 'N/w2LF5v4j8ERayKENPt0MWFFAW3WHTqDLxZ+dqj21I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}