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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b139c20aff364d96972577355cbec6c42d308bee434c2ecbbdcb3aa34ae2b7' 
  AND token = 'uVZowH6QZtC8M6acdWtN72if2+8IdPEA39pP3LOde2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}