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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6effd4493e0f897602d7122da7a133ce02a33517ee58f9a631840ad29b76dfd0' 
  AND token = 'AMd/Z7ZGKmO3nObfk1sxzXqrV/DKJSHW5zOIOWOYp2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}