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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c868c7294fa45c24dec5a8aaa52865d04e53e414c433666c1bc71387f6a39b45' 
  AND token = 'X4wjdeqo/RivfQ4JCfeM2ML5YCNF+tTRh6MudytW0t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}