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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9756ff4dba64984a3f368df4b49f9643f0f5678bf2c9bc300befcc89db25e369' 
  AND token = 'p8G84Eb+vJQQQJSopltMN8B1o8t+uhjesDPRsK3FA2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}