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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec53b06f9eb2c613ae6103d84be7a18cdcfd085caffd8d68372323ed9e240099' 
  AND token = 'kcFKFHpt6vZToEkKhPZ7AFPXRNh33V/doNJ4iuOcLOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}