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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ce141915361b55bf7453fdadb147f6ca6c259db0dee8dab60fccc73b13e74e' 
  AND token = 'HE9xSEJBfagp0WL2PdChqZ6dqGpZmI9xeSnnX5+m2ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}