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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b446e87d997f8f29fd928db5f68ee7fe2f399cfbce31562f2b723f5653858c18' 
  AND token = 'zynrwLXtUCoB/seiaPl76AnlH4dsZyHjYIW7Sxrdx3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}