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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66faac52c285f6e230e20962e808698e08f8c9af164f707a518cb4f07b0319a3' 
  AND token = 'xbrsO4rgMAb550/K/g+WilSvpBk7qwi9/FtM0X66x7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}