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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424c56a1652a7cb3ecbe437946e173a28da1e9e1de3f9599032aa8e1823307e8' 
  AND token = 'r7lLa/EubUqN/VkCYTPJuxU4rYFhHcqfgeVGIXAQYc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}