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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677649e4d6d984c0d585f779f4afbb666f0c4cb5a493c6c0be78590d6ac0ee75' 
  AND token = 'N3S0xpeXF0d5EooesqGf/CiwaVPg4dFZIBrFhlFYAQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}