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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8788ed1974feb744daa88d2cd64497f36be4aede2f00d017a46ff4e4285c904d' 
  AND token = '7Rixda5Ak1R2A4FkVAlAUg9nd1vGWxdZ0dhk+eC1wds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}