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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387fc06baa9dae9e18e93b7c9f90df4afdb03b9ce219ca6f040196259d85fdf5' 
  AND token = 'Q6+YWFW9eQgo2pqfCkmkVdH+ugnGucwOlaCGCRfhM8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}