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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0500116c412fbe0d6b2926fb1c1a1cc63f673580c0d4df9ea4ff53483262e5a' 
  AND token = 'WveudGks/Z1CpwrrOlVx05vpUwXSGZzf6D3d6DRrjr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}