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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ceef9914f5f11f589dbc4c6e977b6a104bab11ce7cd9a9f891771b2251b2a7' 
  AND token = '21PgBPJ2xD7sl2z6/RaxFQ+uU6EhN3baRZCFXMTK7BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}