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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f12ef503f53c391903f7a57f0caa86d01b06a27e43ea4e4c6d73d467ff9058' 
  AND token = 'oXk+xGRQb2xP3dGXrR88sInfLzmofTe68kOksWA6vKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}