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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ead9df046166a712dbcce003499c073ccdf0f3326bc51aaf5b79f348d4ae80' 
  AND token = 'H9eejArQB0EohE+1BOTn+gRuvBuF636nZtSYlvcT92E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}