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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2142cfe9cc5fd0a61c5d8f091dbfab15c93cf30175b23052f095088696eb8725' 
  AND token = 'KxJ3xMsnefnj4U2tckuOn5rXbzK39T3YKoh5iDZs/BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}